How can we modulate aging?

 Aging is a complex time-dependent multifactorial biological process, involving a gradual decline in cognitive and physiological functions over time. 

This results in a reduced capacity to respond to stressors, which in turn increases morbidity and mortality [1–3]. 

Pathological phenotypes associated with aging 

include frailty (a condition associated with progressive physical and mental decline [4], 

chronic medical conditions, such as diabetes and cardiovascular disease [5, 

6], visual impairment, for example age-related macular disease [7, 8], cancer [9], 

and neurodegenerative disorders, such as Alzheimer’s, Parkinson’s and Huntington’s diseases [10, 11]

, to name some of the most prevalent.

Ref

Aging (Albany NY). 2023 Apr 20;15(8):3191–3217. doi: 10.18632/aging.204668

How can we modulate aging through nutrition and physical exercise? An epigenetic approach

Ana Teresa Rajado 1,2, Nádia Silva 1,2, Filipa Esteves 1,2, David Brito 1,2, Alexandra Binnie 1,2,3,4, Inês M Araújo 1,2,3,5, Clévio Nóbrega 1,2,3,5, José Bragança 1,2,3,5, Pedro Castelo-Branco 1,2,3,5,✉; ALFA Score Consortium*