Corona Smoking Relation

Corona Smoking Relation 

In 1604 James described Tobacco

As 'Hateful to the nose ,harmful to the brain 

And dangerous to the lungs:'

Lung cancer pneumonia Asthma  COPD chronic obstructive pulmonary disease are common among smokers.

Let us therefore understand  Corona relation to smoking .

Corona virus or Covivid  19 virus enters through nostrils or mouth and passes through 

Trachea wind pipe to alveoli ( it looks like a bunch of grapes ) alveoli are air sacs filled with gasses. Alveoli is plural single air sac is called 

Alveolus .It has internal wall like structure also called membrane or a wall  made up of two types of cells  1) Type 1 Pnumocyte which work as gas exchanger  oxygen is handed over to Red Blood Cells and  carbon dioxide  from RBC

Is taken for disposal via trachea.

2) Type 2 Pnumocyte they act as surfactant ie preventing  alveoli collapse.

It is usual social experience  when on birth day air filled balloon when collapse children cry.

But it is easy to  refill balloon but once our ir sacs collapse it'd a serious issue.

Ok we know corona virus is  interested in winning  situation so corona is not just happy 

To just stand in side but interested  in entering   wall cells and that to surfactant functioning cell  Type 2 Pnumocyte 

Let us understand this above cell is having a receptor or door called ACE 2

Through this door virus enters and removes it's RNA and via Ribosome machinary gets virus copies like a Xerox machine corona uses

Host machinery to multiply grow .Finaly

Host immune system try to attack virus but

As surfactant function is lost  cells collapse immune system attacks their own cells  finally oxygen is reduced patient needs oxygen in  few patients  some may require ventilators.

 Having understood this a collapse of balloon of alveoli

Let us compare what happens if corona patient is smoker in a smoker patient Ace2 doors increase it is called upregulation this is golden opertunity for virus as many doors are open for virus.

Therefore smoking is not good as it helps the Corona enemy . 

Ref  Breake S J et al J Clin Med 2020 :9(3)841

Published March 20