Sunday, September 20, 2020

Corona(Covid 19) and Lymphocytopenia

 Covid  19  cases in India 

March 7    news from Maharshtra  Times 

India  Corona (Covid 19 ) cases 31

Today  Corona (covid 19)crosses  54 lakhs 

We are going to study  a blood test which 

Would tell us severity of Covid 19 which would 

Give a guidelines for treating  Covid 19 patients

Let us know what are WBC  let us  know 

These  are part of the blood cells  called white 

Cells or leucocytes generally famous for fighting the diseases .

The  different cells make different types  of WBC

1 )Lymphocytes 2) Neutrophils 3 ) Eosinophils

4)Monocytes 5)Basophils 

We will concentrate on lymphocytes

Lymphocyte  give us immunity. Innate immunity

By T lymphocytes  , and adaptive immunity

By B lymphocytes.

Lymphocytes number range from 25% to 40%

Among WBC

When   lymphocytes are less than 25

A term used is lymphocytopenia

In  Covid 19 patients if lymphocytes are below 25 Covid 1 9 patient suffers from lymphocytopenia  this predics disease severity

Of Covid 19

Lymphocytopenia   may results due to

1) The virus might directly infect lymphocytes

  Resulting in death of lymphocytes as and thus 

Reducing number of lymphocytes

2) Inhibition of lymphocytes due to hyperlactic acidemia.

3) Lymphocytes express Corona virus receptor

    ACE 2 and may be direct target of viruses.

Ref  Li  Tan et al 

Signal Transduct Target There 2020 5  33

Online 2020 March 27 


 






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