Homocysteine Blood Test

 Homocysteine   

Blood   Test

Homocystine  first described in 1932

By Butz and du Vigneaud .

Homocystine (Hcy) is a sulphur containg amino

Acid that is closely related to essential amino acid methionine and cysteine.

Folic acid vitamin B12 and Vitamin B6 are essential in maintaining normal Hcy levels.

Fasting Ref(1) blood is taken for Hcy test.

Normal range 5 to 15micro mol/L

16 to 30  micromole moderate

31 to 100 micrro mol e intermediate

Above 100 micromole severe

Hyperhomocystenemia rise  due to deficiencies 

Of folate vitamin B12 and Vitamin B6.

Hyperhomocystenemia is observed in 

1 Cardiovascular disease

2 Heart attack

3 Hypertension

4 stroke

5 coronary heart disease

6  Atherosclerosis

McCully in 1969  first reported hyper homocystenemia  in atherosclerosis.

Ref (2)Allan D Kaye et al 2020 

Reported folic acid supplementation 

In patients with elevated homocysteine levels.

Folic acid 0.5 --- 5mg typically lowers

Plasma homocysteine by approximately 

25%

Folic acid may likely reduced vascular disease

Folic acid supplementation should be recommended to any patient who has an 

Elevated homocysteine levels.

In the early 1990s Homocysteine become

A recognized risk factor for atherosclerotic disease . For atherosclerotic disease Homocysteine levels greater than 15 micromoles/ L

Ref 1 Paul Ganguly and Streyyoshi Fatima

Alam

Nutr J 2015 :14 :6

Published On line 2015 Jan 10

Ref 2 Alan D Kaye , 

          George M Jeha ......and Christopher 

          G . Keval

          Adv Ther 2020 :37(10):4149--–4164

Published on line 2020 Aug  

Please note do not follow 

 Any information without consulting your

Doctor or Family Physcian