Saturday, March 11, 2023

H3N2 Human Influenza

H3N2 Influenza IN Humans

Today we will learn some basics about H3N2
Recently news paper cover this influenza news

Influenza History : IN 1968 a

Novel  strain of H3N2 emerged  in Hong Kong

(A Hongkong/1/1968)(HK/68)

That quickly led to a global epidemic that
Was associated with more than one million
Deaths world wide.

 Symptoms: fever sore  throat 

Coughing nasal  discharge headache 

And myalgia .Severe cases can also

 lead to development of conditions


Such as bronchitis or pneumonia .

In 1968 an Avian reassortant virus of the H3N2
Subtype was introduced into the human
Population that cause a Global pandemic
Associated with more than one million 
Deaths world wide.
Since introduction in1968 H3N2  influenza viruses have undergone an extensive 
Genetic and antigenic evolution leading to

28 vaccines strain changes(This is strength

Of virus)


Over that period of time .

H3N2 influenza also altered  receptor

Binding properties over half century

Poor efficiency  nearly 28to42%
For all age groups in US
And in Europe 

The WHO. Meets twice a year to recommend


In seasonal influenza vaccine


Ref  Hum vaccine Immunotherapy
       2018:14(8);1840---1847
       James D Allan and aTed M .Ross











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