Lung Cancer

    Lung Cancer 

Lung cancer is the most frequent  cancer and

Leading cause of cancer death worldwide .

              Types

     1)Small Cell Lung  Cancer (SCLC)

           15% of Lung Cancer

      2) Non Small Cell Lung Carcinomas

           (NSCLC) 85%of all lung cancer 

                           NSCLC sub Types

           1.    Squamous Cell Carcinoma

            2 Adenocarcinoma (AD)     

             3 Large Cell Carcinoma(LCC)

             Five year survival 

            SCLC  if limited disease

               30% 5 Year survival For extensive 

Disease SCLC 10% survival for 5years

               NSCLC     survival foR 5 years

Depends on the spread of cancer

Stage1 A survival 90 %

Stage 4  survival below

 10% for 5years.

Risk factors for Lung Cancer

1 Cigarette  smoking being a major factor.

2   Up to 20% of cancer deaths world wide

      Could be prevented by tobacco smoking  Elimination.

3  At least 50 carcinogens has been identified

     In Tobacco smoking.

4    Global statistics indicates  that Lung

        Cancer In Never Smoked (LCINS)

         Accounts for 20% of Lung Cancer

        At least 17% of  LCNS are attributable

     To exposure to high level of environmental

Tobacco Smoke (ETS) or to second hand smoke

 

         24% excess risk for lung

      Cancer is found in non smokers who lives with smoker .

5 The incidence of  lung cancer without

   Tobacco smoking history is increasing.

   The polluted air especially particulate

 Matter 2.5 (PM2.5)has been indicated

As the major factor for LCNS incidence.

Ref Mol Cancer 2021:20:22

      Ming-yue Li 

       Li-Zhong-Liu and

        Ming Dong