Corona (New Forms)

 Variants are new Forms

Variants emerge due to mutations

What are mutations , mutations are

Sudden changes .

 All mutations are not variants

Mutation is structural change

But when structural change results 

In functional changes it is variant 

Example Britain Variant spreads faster

Compare to Sars CoV 2 

Mutation is sudden change like

A typist accuracy may be 1000 words 

Or 10000

But may make a mistake 

Variant results with structural and functional 

Change 

This is genomic change genome is genetic

Information 

Sars CoV 2 virus has approximately 30000

Genetic pair bases eg AT GC

Corona virus is RNA virus so T is always 

Replace by U

So genomic language is five letters

AT GC and U

A for adenine

T for Thymine 

G for Guanine

C for cytosine

U for uracil

All above five are nucleobases 

These letter code  give rise to amimoacids

These join and make various protein

By using 3 letters from above  specific amino acid is formed

Any mistake resulted is mutation.

For eg AGU code forms Serine a amino acid

If due to mutation A is added

New triple code is AAG  forms lysine an amino

Acid

Variants are formed in due to many specific 

Mutants which make virus more affinity

In binding ace2 receptor It is

Simple to understand  mutation 

Suppose spelling of CAT written  as CAR

By replacing T with R 

Or Spelling of GIVE is written as FIVE by replacing G   by letter F meaning is changed

Similarly virus new forms show 

Structural changes resulting in new form

With different function.

MASk MASK.MASK is important to get 

Protection from new variants