Ref 1 Oxid Med Cell Longev
2019 :2019:8267234
Rosa Vona
Lucrezia Gambardella
Camilla Cittadini
Elisabetta Straface. And
Danatella Pietra Forte
Metabolic Syndrome
Metabolic Syndrome represents worldwide
Public health issue , characterized by a set of
Cardiovascular risk factors including obesity,
Diabetes , dyslipidemia ,hypertension and
Impaired glucose tolerance.
Metabolic syndrome is a risk
Factor for type 2 diabetes
,Cardiovascular disease
and premature mortality
Ref 2 Current Hypertension Reports
2018:Feb 26 doi 10,1007/s 11906-018-0812-2
Saklayen Mohammad G
Metabolic Syndrome known as Syndrome X
,Insulin resistance
WHO Def :Pathological conditionCharacterized by abdominal obesity insulin resistance hypertension and hyperlipidemia.
Basic forces spreading this malady
1 Increase in consumption of high calorie
---low fiber fast food.
2 Decrease in physical activity due
Mechanized transportations and sedentary
activities.
Syndrome --Spread Type 2
Diabetes Coronary
Diseases , Stroke
Among all non communicable diseases
Metabolic syndrome had been the real
Scourge globally.
Metabolic syndrome ,syndrome X,
Insulin resistance Defined
As per NCEP; National Cholesterol Education
Programs ATP3 2005
Presence of any 3 or more of the
Following
1 Blood Glucose greater than 100mg/dl
Or drug treatment For elevated blood
Glucose .
2 HDL Cholesterol less than. 40mg/dl
In men
Less than 50 mg/dl Women
Or drug treatment for low HDL Cholesterol
3 Blood Triglycerides greater. Than
150mg/dl or drug treatment for elevated
Triglycerides.
4 waist greater than 102 Cm men
Or 88cms (women)
5 Blood Pressure greater than 130/85 mm Ng
Or drug treatment for Hypertension
Epidemiological studies
Have shown association between
Intrauterine nutrition Mothers exposed
To Dutch famine of 1944-1945
During the first two trimesters of the
Of the pregnancy had babies with low
Birth weights .But these babies had higher
Incidence of obesity in adult life .
Prevention :
Physical activity and exercise are key
Components of energy expenditure and
Energy balance .
Western lifestyle increased use of
Automobile and more time spent indoor
Watching TV or playing video games.
Increased sedentary life style is major
Driving force for increased Metabolic
Syndrome prevalence.
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