Smoking and Brain
Stroke
WHO reports every year approximately
15million people have a stroke
87% Ischaemic Stroke
10% Intra cerebral Hemorrhagic Stroke(HS)
03%. Subarchnoid ( HS)
20.8% US populations are smokers.
(Ischaemic stroke : caused by deficient
Blood and oxygen supply to the brain
Hemorrhagic stroke : is caused by bleeding or leaky blood vessels.
Ref Int J Mol sci 2020
Oct :21(20):7609 Diji Kuriakose and
Zhicheng Xiao) )
Meta analysis
Results
14 studies 303134 subjects
Results Smokers had an over all increased
Risk of stroke compared with non -smokers
With pooled odd ratio (OR)of 1.61(95%)
Confidence interval CI;1.34-1.93
p less than
.001
Passive smoking increased the overall
Risk of stroke by 45% (OR:1.45,
95%CI 1.o---2.11 p less than .05)
Conclusions : On the dose response
Meta analysis the risk of stroke increased
By 12 %for each increment of 5 cigarettes per day.
Ref. Medicine (Baltimore) 2019 March;
98(12):e14872
Biai Pan
Xiao Jint
Liu Jun, Shaohong Qiu
Qiuping Zheng and Mingwo Pan
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