The Impact Of Coffee Intake
The conception of There consumption has undergone
a profound modification ,evolving from noxious
Habit into a safe life style actually a preserving human health
The last 20years also provided strikingly consistent epidemiological evidence
Showing that the regular consumption of moderate doses of coffee attenuates
all cause mortality an effect observed in over 50 studies indifferent geographical
regions and different ethnicities.
Impact of Coffee intake on Longivity
Coffee is the most consumed beverage after water with
2.5 billion cups consumed every day.
Coffee is a mixture of over 2000 potentially bioactive
Substances with particularly high levels of chlorogenic acids
And caffeine and with other substances .Such as melanoidns,
Diterpenes and Trigoneelline.
Several beneficial effects have been associated to
melanoidins Such as antioxidant ,antimicrobials , anti-inflammatory,and probiotic Activity .
Coffee Intake and life span
In fact epidemiological studies concur in deducing
That regular consumption of moderate doses of coffee is
Associated is with an increased life span.
Conclusion emerging from both meta-analyses
And narative reviews .
This association was noted in over 50 different cohort analzed
In different geographical locations notably stronger associations
are found in Europe and Asia than in US.
Who benefits from the impact of coffee on life span?
The risk ratio linking coffee consumption and all cause mortality
Is computed between 078and 0.94
(Means no association and values below 1 means on increasingly
Stronger inverse association) These values of risk ratio correspond
To an estimated 15,%lower likliness of dyeing during analysed
Periods to gain of 1.84years of life expectancy to coffee intake
Using Chiangs life table or 4.70-9.1%of estimated years of life
It is important to keep in mind hat odddds ratios are average
Values applicable to whole population studied ,where some more
Individuals benefit by drinking coffee where as others may suffer
Deterimental effects upon coffee consumption , in accordance with
Inter individuals differences in caffeine .
Increased life span attributed to coffee consumption is observed
In men and women.
Dose dependent effects of coffee
On life span
Accordingly several epidemiological studies and meta studies and meta analysis
Concluded that benefits of coffee consumption on life span follow a J shaped curve
With discrete benefits afforded.
The consumption of 1cup of coffee a day , maximum benefits afforded by 3cups
a day followed by waning of the benefits with increasing doses of coffee consumed
Daily
Negative impact of high doses of coffee
Intake on behavior of adults ,typified by symptoms such as heightened anxiety
Agitation restlessness headache , insomnia and gastric distress .
Coffee intake attenuates age associated diseases .
Coffee intake preserseves the main biological mechanisms of aging
Ref Aging Research Reviews vol 102 Dec 2024 , 102581
Catia R Lopes
Rodrigo A Cunha
