Apples
Apples represent 12.5% of all consumed
Fruits in the world because of their health
Benefits ,taste .
Epidemiological studies suggest that a frequent
Apple intake is inversely associated with
Acute coronary syndrome ,total CVD mortality
And all cause mortality.
All above advantages are behind the
Saying an Apple a day keeps the doctor away.
Bioactive components polyphenols include
Flavanols (catechin and proanthrocyanidins)
These may be responsible for potential
Health effects.
Apples are an excellent source of polyphenols and fiber.
Apples consumption or their bioactive
Components is beneficial on lipid metabolism
And other markers of cardiovascular disease.
The clinical trial was conducted (Ref1)
It was randomised controlled crossover
Intervention trial. Apples use (Renetta Canada
2 daily for 8 weeks each separated by 4wk
Wash out period .) Apple control beverage
CV)
Results : Whole apple consumption decreased
Serum total cholesterol 5.89mmol/L: CB
6.11mm/L :p=0.006
And LDL cholesterol (whole apple
: 3.72mmol /L:CB 3.86mmol/L:p=0.031)
CB means control beverage.
Triacylglycerol (wA :1.17mmol/L:CB
1.30 amol/L: p=0.021 )and
Intercellular cell adhesion molecule -1
(WA:153.9ng/mL:CB :159.4ng/mL: p=0.028)
And increased serum uric acid
(WA:341.4,Micromole /L : CB:330 micro mol
/L: p=0.020 )
Compared with the CB the response to endothelium dependent microvascular
Vasodilation
Was greater after the apples (WA:853
Perfusion units (PU ),CB :760 PU ;p=0.037)
Than after CB .
Apples had no effect on blood pressure
Or other CVD markers.
Note: WA : Whole Apple
CV : control beverage
Conclusions : These data support beneficial
Hypocholesterolemic and vascular effects
Of the daily consumption of
proanthrocyanjdins rich apples by mildly
Hypercholesterolemic individuals.
Ref 1 Am J Clin Nutr 2020 Feb :111(2):307-318
Athanasios Koutsos
Samantha Riccadonna
(.......)and Julie A Lovegrove
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