Leukemia & Benzene

Term carcinogen means which causes

Cancer now Benzene is a chemical

Carcinogen

Bone marrow is crucial for blood cells

Manufacturing

Excessive exposure to Benzene is known

For more than century to damage bone marrow.

Since late 19th century benzene is used

Commercially affects the health of large

Number of workers.

Exposure Benzene

Low : Thought to be without effect in humans

High: many hundred parts per million

Result workers displaying decrease in

Number of Erythrocytes ,leukocytes

And /or Thrombocytes in circulating

blood.Results in Pancytopenia

And aplastic anemia.

Bone marrow is a target organ for Benzene

Toxicity.

Benzene induced decrease in blood cells be observed within a few months

After after exposure initiation.

However there is lag time of perhaps

Years between initial Benzene

Exposure and the development

Of leukemia

Int J Environmental Responsibility Public

Health 2012 Aug:9(8) 2875----2893

Shreeram