Kidney Function Test (Serum Creatinine )

     Kidney Function Test (Serum Creatinine) 

          The kidneys are the waste management  system of the body ,removing excess fluid

   

         and toxins from the blood stream and filtering them into urine .

           If kidney function is significantly reduced and patient develops ,ESRD End Stage 

.          Renal Disease.This.situatiom is life threatening and kidney transplant or regular 

          dialysis treatments  are.only options.

        

        To understand the Serum creatinine test ,we should know few terms first what is 

       

         Serum ? The serum is the fluid and solute component of blood after clotting.

         What is creatinine ?

         Creatinine is breakdown product of muscle metabolism in the body .Measuring serum

  

          Creatinine is useful method of evaluating  kidney dysfunction .

          Renal(kidney) dysfunction diminishes the ability to filter creatinine and thus Serum 

         Creatinine rises.

            If serum creatinine  level doubles , the GFR Glomerular filtration rate considered

            To have been halved .A three fold increase of creatinine increased is consider to 

             Reflect a 75%  loss of kidney function .

              Reference values Serum Creatinine 

                Adult Males.     0.8-1.4mg/deci liter

                Females.           0.6-1.1mg/deci liter 

               Values are slightly higher in.males as they have larger muscle mass


            To  know what is Glomerulus 


             Each kidney is having 1million  functional small units called nephron ,

              Functional unit starts with filter called Glomerulus 

                    Ends with tubule.