Triglyceride Glucose Index

Triglyceride Glucose Index is useful since it is simple surrogate marker for insulin resistance. 

Ref 1 kim et al 2017 Cardiovascular Diabetology (2017)16:108

     

Kim et al 2017 

       Triglyceride Glucose Index has been considered a simple surrogate marker of insulin resistance. 

        Kim et al 2017 concluded that TyG index is more independently associated with the presence of coronary artery atherosclerosis.

        Ref 2 PLOS One.2016:11(9):e0163465

       

         Da young Lee ,et al 

Da Young etal 2016.R2016.Reported subject with high TyG index had a high Risk of diabetes

Sub groups with TyG Index greater than or.equal to.8.8

Regardless of obesity had a significantly high Risk of diabetes (HR 2.4 p =O.024)

And 2.25 for obesity p=0.048

   Determination of the TyG index was based on the formula 

     Ln (Fasting Tryglyceride (mg/dl) x Fasting Glucose mg/dl)/2

    Ref 3)

Lee SB ,Ahn CW ,Lee B k, et al 

Association between Triglyceride Glucose Index and arterial stiffness in Korean adults 

  Cardiovasc Diabetol 2018 : 17(1) 41

Published 2018 March 21 

The TyG index is more independently associated with increased arterial stiffness than HOMA-IR in Korean adults.

Arterial stiffness measured on brachial ankle pluse wave velocity.(bapwv)

 The TyG index is useful as insulin test is costly . 

How to calculate TyG Index?

Ln(Triglyceride fasting mg/deci lit x1/2 fasting glucose )

 L et us solve one example  suppose Triglyceride fasting 200 mg /deci lit

     Fasting blood Glucose 130mg/deci lit
 

         300x130/2=19500
   

      Log e 19500


     refer net.to calculate

             And 9.87 and above 8.8 so high Risk for diabetes even 8.8 is risky number
   


      Less.than 8.8 TyG index is.safe normal .