Pancrease Insulin Factory
The Factory is famous for insulin production.
Length of Factory is just 15cms
And weight not so heavy even the Child
Of 2years could lift the factory easily
As it is just 80grams only.Ok
Let us visit the factory where it is located,?
When food comes through food pipe (esophagus )
food enters stomach
So
Factory is now very closed by It is situated back side
of stomach in the gap
Of the C shaped of small intestine.
The factory shaped is like Banana leaf .Arranged
horizontaly from tip of
Of the leaf called tail .The duct like structure of the leaf
is like the duct of
Pancrease which carries pancreatic juice useful for digestion.
Two Divisions of factory
1Exocrine gland this produces pancreatic juice which
Helps in digestion
2Endocrine gland this is duct less gland This Division produces
Hormones Insulin and Glucagon.Timely need based secretions
The workers job nature
Three types cell types
Alpha
Beeta
Delta
Alpha :produce Glucagon
Beeta cells :Job produce Insulin
Delta :Suppervision
Hormones production Division is called Islets of
Langarahance
Paul Langherance in the year 1869. Put section of pancrease
Under the microscope he observed microscopic islands
Later called Islets of Langarahance since he discovered islands.
Guess the number of islands may be thousand Tenthousands
No 10lac is the right number
Each Islet compose of Alpha cells 30% Beeta cells 60%
Delta cells 10%
There are 10Lac islets in entire Endocrine gland.
The endocrine gland weight is 1-2% compair to pancrease weight
Of 80grams.
It means weight of endocrine gland is between 0.8gram
To 1.6grams
A thought comes if endocrine portion was slightly more even say 2
grams or so
It means more insulin more insulin better sugar controlled
may be we could eat
More sweets.
But while nature thought sugar was not in existance.
sugar was introduced around 2500 years ago in India.
Let us know about Beeta workers (cells)job
These workers work for 24 hours
Every 10 to the 15 seconds blood sugar is sensed
Any time sugar is sesenced above 140mg %
Then delta cells give action within 1 to 1.5minutes
To control blood sugar levels. Beeta cells produced insulin
If required.
Every cell in the body requires glucose .what we eat as
Carbohydrates gets converted after digestion to glucose
Glucose comes in to blood stream.
But glucose cannot enter the cells eg muscles unlessl
Insulin pushes it.
But due to insulin resistance glucose cannot enter in to the cells.
Insulin islike a broken kety in resistance case.The sugar remains
in blood stream. So lots of sugar is pushed in liver by Glucagon
In the liver and gets pack ss glycogen.so the blood sugar is controlled.
Daily routine work use glucose if glucose levels fall
Delta workers give order so alfa workers so that glycogen pack is
unpacked into glucose and release in blood stream so that
Hypoglycemia is prevented. Blood sugar is kept under control.
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