Sunday, July 21, 2024

Pancrease Insulin Factory

  Pancrease Insulin Factory 

The Factory is famous for insulin production.

Length of Factory is just 15cms 

And weight not so heavy even the Child

Of 2years could lift the factory easily 

As it is just 80grams only.Ok

Let us visit the factory  where it is located,?

 When food comes through food pipe (esophagus  )
food enters stomach
So 
Factory is now very closed by It is situated back side 
of stomach  in the gap
Of the C shaped of small intestine.
The factory shaped is like Banana leaf .Arranged
 horizontaly from tip of
Of the leaf called tail .The duct like structure of the leaf  
is like the duct of 
Pancrease which carries pancreatic juice useful for digestion.

               Two Divisions of factory

       1Exocrine gland this produces  pancreatic juice which
      Helps in digestion 
         2Endocrine gland this is duct less gland This Division produces 
    Hormones Insulin and Glucagon.Timely need based secretions

      

               The workers job nature

Three types cell types
Alpha
Beeta
Delta
 Alpha :produce Glucagon 
Beeta cells :Job produce Insulin
Delta :Suppervision

     Hormones production Division is called  Islets of
Langarahance 
   Paul Langherance in the year 1869. Put section of pancrease
Under the microscope he observed microscopic islands 
Later called Islets of Langarahance since he discovered islands.

Guess the number of islands may be thousand Tenthousands
No 10lac is the right number 
Each Islet compose of Alpha cells 30%  Beeta cells  60%
Delta cells 10%
There are 10Lac islets in entire Endocrine gland.
The endocrine gland weight  is 1-2% compair to pancrease weight 
Of 80grams.

It means weight of endocrine gland is between 0.8gram 
To 1.6grams

A thought comes if endocrine portion was slightly more  even say 2
 grams or so
It means more insulin more insulin better sugar controlled 
may be we could eat
More sweets.
But while nature thought sugar was not in existance.

sugar was introduced  around 2500 years ago in India.

Let us know about Beeta workers  (cells)job 

These workers work for 24 hours 
Every 10 to the 15 seconds blood sugar is sensed

Any time sugar is sesenced above 140mg %
Then delta cells give action within 1 to 1.5minutes
To control blood sugar levels. Beeta cells produced insulin
If required.
    Every cell in the body requires glucose .what we eat as
Carbohydrates  gets converted after digestion to glucose 
Glucose comes in to blood stream.

But glucose cannot enter the cells eg muscles unlessl
Insulin pushes it.
But due to insulin resistance glucose cannot enter in to the cells.
Insulin islike a broken kety in resistance case.The sugar remains
 in blood stream. So lots of sugar is pushed in liver by Glucagon 
In the liver and gets pack ss glycogen.so the blood sugar is controlled.

Daily routine work use glucose  if glucose levels fall  
Delta workers give order so alfa workers so that glycogen pack is 
unpacked into glucose and release in blood stream  so that
Hypoglycemia is prevented. Blood sugar is kept under control.











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